Armodafinil vs Modafinil

Armodafinil vs Modafinil

The market is over-flooded with nootropics that have the ability to enhance people’s cognitive skills and improve their memory, mood, and motivation. That’s why choosing the right one for personal use can be quite a challenge. 

In order to help you with that, we first wanted to point out all the similarities and differences between Modafinil and Armodafinil drugs, since those are the nootropics people are most interested about, and to establish who should be the winner in Armodafinil vs Modafinil battle, and therefore your pick. 

But first, let’s find out when and why these nootropics are being used.

This article and all other content created by Moda Wiki is for informational purposes only. It is created for your entertainment. This is not legal or medical advice. Always make sure to seek the advice of your primary physician or medical professional before consuming nootropics, like Modafinil, or other pharmaceutical drugs. Please read our disclaimer.

Both Modafinil and Armodafinil are wakefulness-promoting agents that were designed for treating symptoms of several sleep disorders – narcolepsy, obstructive sleep apnea, and shift work sleep disorder. We are talking about FDA-approved medication that has the ability to put a stop on excessive daytime sleepiness and fatigue that are the usual consequence of these conditions. They are suitable pharmaceuticals for promoting full wakefulness and preventing daytime drowsiness.

But besides for these on-label purposes, Modafinil and Armodafinil are often being used for treating ADHD (Attention Deficit Hyperactivity Disorder), as well as for cancer patients who are suffering from fatigue caused by the chemotherapy. There are studies that show these nootropics can be quite effective in facing daytime sleepiness in people with multiple sclerosis, but it is underlined that Modafinil and Armodafinil should not be reached for as a first-line option for this disease.

Now, it is a well-known fact these smart drugs are being taken by students, programmers, and other ambitious professionals who would like to enhance their cognitive skills because Modafinil and Armodafinil have the ability to improve our memory retention, our focus, concentration, and motivation, but also to affect our mood. The exact way these drugs are working is yet unknown, but what is familiar is that they are boosting dopamine activity in our brain that leads to these results.

Differences between Modafinil and Armodafinil

Both Armodafinil and Modafinil are central nervous system stimulants that are considered to be safe and effective smart drugs. Even though they have the same active ingredients, their structure is a bit different. Armodafinil is a newer drug if we compare it to Modafinil, it was approved in 2007, while Modafinil has been in usage for around 30 years now. 

It seems like the most significant difference is the duration of their action, and the fact Armodafinil is a bit stronger and more powerful than Modafinil. That’s why the 200mg of Modafinil is equivalent to 150mg of Armodafinil. Also, Armodafinil has a bit longer half-life, and it will stay in your system for an hour or two more than Modafinil.

Which one is more effective?

According to most clinical trials that were conducted in order to establish which one is more effective – Modafinil or Armodafinil, they are both pretty equal in that matter. When it comes to treating symptoms of narcolepsy, SWD, sleep apnea, and other sleep disorders, both of these nootropics have the ability to help a person deal with excessive sleepiness and fatigue. 

But the fact is Armodafinil is a slightly more potent drug. It has a longer-lasting effect and higher plasma concentration in the body, which means that it probably has a better wakefulness effect than Modafinil. However, given that each individual reacts differently to smart drugs, these are not exact assessments we can rely on. 

Some people claim Armodafinil is an absolute winner in the Modafinil vs Armodafinil battle, while others explain Modafinil helped them when Armodafinil couldn’t.

Recommended dosage and price

The recommended dosage for off-label usage of Modafinil is 200mg a day, while for Armodafinil is 150mg. We are here talking about taking these nootropics as cognitive enhancers and memory improving tools, not as pharmaceuticals used for treating sleep disorders. If that’s the case, the doctor will prescribe the right dosage for each patient based on the condition he is suffering from, his medical history and overall health condition.

People who are first starting with a smart drug usage can take lower doses, like the half of the one that’s recommended, just to allow their bodies to adjust to the effects Modafinil and Armodafinil can bring in. The results will be the same, they will have their performances significantly improved, but for a shorter period of time – instead of experiencing benefits of these nootropics for 12 to 15 hours, they will be enjoying them for six to nine hours straight.

Now, when it comes to the cost of Armodafinil and Modafinil, we have to say that their prices can vary a lot, depending on whether you are buying a brand name or generic versions of these smart drugs, and whether or not you are covered with insurance. On average, one Modafilin pill of 200mg costs around 25 dollars, while an Armodafinil pill is a bit more expensive and goes up to 30 dollars. 

But we are talking about brand names – Provigil and Nuvigil. Generic versions of both drugs are more affordable – you can find a generic version of Armodafinil for only seven dollars, and Modafinil pills for 10 dollars. Bear in mind that Modafinil and Armodafinil can be fully covered with insurance if they are prescribed by the doctor.

Modafinil and Armodafinil Side Effects

The next thing you are probably wondering is what’s the deal with Modafinil vs Armodafinil side effects. The truth is, they both can lead to several similar conditions that are not something you should worry about, like headache, dizziness, nausea, diarrhea, insomnia, anxiety, dry mouth, and agitation. 

These are the common side effects that will be present for some time and can be easily handled. Now, when it comes to more serious Modafinil side effects, some reports show people were having troubles with fever, back pain, chest pain, increased blood pressure, hallucinations, irregular heartbeat, depression, or easy bruising and bleeding. 

Those are extremely rare, but if it happens that you face some of them, you should immediately stop using this nootropic and seek medical help. With Armodafinil, there are chances of some mental and mood changes, irregular heartbeat, or shortness of breath, but again, in general, that’s very rare. According to research, Armodafinil users have lower chances of experiencing side effects.

Drug interactions

It turns out that both Armodafinil and Modafinil have similar drug interactions. In general, you can consume Modafinil with other medications, but it can happen they affect each other and how they are processed in the body. 

For example, Modafinil can reduce the effectiveness of steroidal contraceptives. If you are using this nootropic for treating certain conditions, it is extremely important to inform your doctor about all the drugs you are currently using, including vitamins, prescriptions, over-the-counter drugs, and herbal products. 

Modafinil has 45 serious drug interactions, 188 moderate drug interactions, and 172 minor drug interactions. Armodafinil also can be consumed with some other drugs, but again, your doctor should be informed of all pharmaceuticals you are currently using. 

This smart drug has major interactions with 13 drugs, moderate interaction with 206 different medications, and minor interaction with 174 drug products.


What is Armodafinil?

Armodafinil is a smart drug that’s designed for treating symptoms of several sleeping disorders like narcolepsy, shift work disorder, and obstructive sleep apnea. It has the ability to stimulate the brain to promote wakefulness while putting a stop on daytime sleepiness. It can be used for its off-label purposes as a cognitive enhancer and improver of memory retention.

What is Modafinil?

Modafinil is a powerful nootropic that promotes wakefulness in people who suffer from extensive fatigue and sleepiness during the day. It is primarily used for treating the symptoms of narcolepsy, SWD, and obstructive sleep apnea, but it can also be prescribed for ADHD. It’s often used by students and professionals for the purpose of increasing focus, alertness, concentration, and motivation.

Which is better - Modafinil or Armodafinil?

It is very difficult to claim which one of these two smart drugs is better or more effective. Every study that has been conducted with the purpose of establishing this came to the conclusion that they are pretty much the same in this matter. One only relevant difference is the fact that Armodafinil is a bit more powerful and has a slightly longer half-life. That means that the effects of this nootropic may last a bit longer than the ones provided by Modafinil.

Can you take Modafinil and Armodafinil together?

Consuming Modafinil and Armodafinil at the same time is not something that’s recommended. They are smart drugs that have the same benefits, so it’s simply unnecessary to mix them. Given the fact they have pretty much the same active ingredients, there is a possibility of you experiencing some serious side effects if you take both of these pills at the same time.

Should I take Modafinil or Armodafinil every day?

It is not recommended to use nootropics of this kind every day because if you do so, you are risking creating lower tolerance to them. That means that after a few weeks or few months of regular Modafinil or Armodafinil usage, their effect can start fading, and you will probably be needing a bigger dosage just to retain the same results. It would be best to take one pill once to three times a week, or only when you need the stimulation of this kind.


  1. Tembe, D. V., Dhavale, A., Desai, H., Mane, D. N., Raut, S. K., Dhingra, G., … & Padsalge, M. (2011). Armodafinil versus modafinil in patients of excessive sleepiness associated with shift work sleep disorder: a randomized double-blind multicentric clinical trial. Neurology research international, 2011.
  2. Comparing Modafinil vs Provigil;
  3. Comparing Armodafinil vs Nuvigil;

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