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Adrafinil vs Modafilin

If you were planning on using some sort of eugeroic, you were probably suggested to start with Modafinil or Adrafinil. If that’s the case, it is important to know how these smart drugs are different and what they can bring to the table, in order to make the right decision on which one to choose.

What you should know right on is that they are both able to provide your brain with enough power to overcome the fatigue and daytime sleepiness that affects your work. According to many studies, eugeroics are substances that have the ability to bring up the level of our cognitive functions, as well as our memory retention and creativity.

That’s why they are being used by students, executive professionals, programmers, and other ambitious individuals who need to bring their performance to the maximum level. But let’s take a closer look at the Adrafinil vs Modafinil issue, and conclude which one is better for you.

This article and all other content created by Moda Wiki is for informational purposes only. It is created for your entertainment. This is not legal or medical advice. Always make sure to seek the advice of your primary physician or medical professional before consuming nootropics, like Modafinil, or other pharmaceutical drugs. Please read our disclaimer.

Given that both Modafinil and Adrafinil are considered to be eugeroics, it is important to start there and explain what eugeroics actually are and how they can serve us. Eugeroics are a class of drugs that were discovered in the 1970s for the purpose of treating narcolepsy, obstructive sleep apnea, shift work sleep disorder, and some other sleep disorders.

We are talking about wakefulness-promoting agents that are targeting specific brain chemicals in the hypothalamus and amygdala and not the nervous system as a whole. Because of that, they work more gradually than other stimulants, and they prevent euphoria or agitation from being the following effect of stimulation. Also, they will lead to long-lasting mental arousal, and not just temporary increased nervous and psychological activity.

Eugeroics have the ability to work as cognitive enhancers, to affect focus, motivation, and concentration in sleep-deprived individuals in the best possible way. They can prevent and remove daytime drowsiness and fatigue, without affecting regular sleep patterns and without causing hyperactivity typical for some other stimulants.

Similarities of Modafinil and Adrafinil

Both Modafinil and Adrafinil are considered to be safe for usage and non-addictive substances. They have some differences but many similarities, so we are going to start from there. Adrafinil is actually a precursor of Modafinil, which means they both have similar mechanisms of action, and pretty much the same effects and benefits

They have the capacity to promote wakefulness in person by selectively activating neurons in our brain and increased levels of norepinephrine and histamine. They will increase alertness and improve memory capacity, executive functions in individuals who are using one or another drug, and their cognitive skills.

It is affirmed that Modafinil and Adrafinil are also increasing the amount of dopamine in our brain, which means they are responsible for mood improvement in nootropic users as well. Now, while traditional stimulants like caffeine or amphetamine are directly stimulating the release of dopamine, eugeroics are increasing dopamine levels by blocking the receptors that are responsible for removing this neurotransmitter from the system. Thanks to that, Modafinil and Adrafinil are less addictive than other stimulants.

When it comes to Adrafinil vs Modafinil side effects, things are pretty much the same in both fields. But the chances of facing side effects from Adrafinil are lower than those with Modafinil. In most cases, when taking Adrafinil, people experienced insomnia, headache, and loss of appetite. 

With Modafinil, there are also possible dizziness, nausea, dry mouth, dehydration, diarrhea, and anxiety. Now, Modafinil can lead to increased blood pressure, chest pain and increased heart rate, while those things won’t happen with Adrafinil. It’s only important not to take Adrafinil regularly with other drugs, because there is a danger of liver damage.

Differences between Modafinil and Adrafinil

As you can see, there are many similarities that connect Modafinil and Adrafinil, but we need to point out all the differences, just so you can easily establish which one of these nootropics would be a better choice for you. 

For starters, Modafinil is more powerful and more potent than Adrafinil, so you will need a lower dosage of Modafinil to achieve the same results as with a larger dosage of Adrafinil. The average dosage for Modafinil is 100mg to 200mg a day, while for Adrafinil, the recommended dosage is 300mg to 600 mg a day.

Also, their half-life and working time are slightly different. Adrafinil will need more time to kick in, but its effects will be noticed a bit faster because it will be more intense at the beginning. Modafinil will start working in a shorter period of time, but its effects will be smoother. When it comes to half-life, Modafinil is there in an advantage as well.

However, the legal status of these agents is what makes the bigger difference between them. Even though the World Anti-Doping Association banned both Modafinil and Adrafinil as performance-enhancing drugs, at this moment, Adrafinil is yet unregulated, so in most countries, you can purchase it over-the-counter without a prescription. On the other hand, Modafinil is categorized as Schedule IV substance in most western states, and it can be bought legally only with a doctor’s note. That means you can get to Modafinil the regular way only if you are suffering from narcolepsy or some other severe sleep disorder.

And in the end, there is the matter of cost. Modafinil, especially the brand name Provigil is pretty expensive, while Adrafinil usually comes with a more affordable price. The truth is, Modafinil can be covered by health insurance, but only in some countries, and only if it’s being used for treating certain conditions. In case you want to use it as a cognitive enhancer, you can either pay its full price or look for a generic version at online stores.

Which one is more effective?

There’s no doubt that both Adrafinil and Modafinil are very effective as wakefulness-promoting agents. They will remove the feeling of daytime sleepiness and fatigue and enhance a person’s cognitive skills. Given that each individual reacts differently to these types of stimulants, some people find one to be a better solution than the other, but there is no clear conclusion on which one is more effective. We can say that Modafinil vs Adrafinil fight is pretty much tie in this matter. But it turns out that effects of Adrafinil are more intense and can be noticed a bit faster than those provided by Modafinil, even though Adrafinil takes a bit more time to kick in.

Which one is better for you?

If you have a certain sleep disorder condition and your doctor prescribed you a Modafinil therapy, then that’s that, you should not be questioning his decision or think about changing the nootropic you are using. But if you are thinking about starting with smart drugs for the single purpose of having your memory, focus, concentrations and overall performance increased, then Adrafinil might be a better choice.

Things are pretty simple – they are both equally effective, and they are both wakefulness-promoting agents that have the ability to affect our cognitive skills and executive functions positively. But the fact is, Adrafinil is not regulated yet, and you can get to it more easily. Every pharmacy is probably having this eugeroic on their shelves, and you won’t be doing anything illegal when purchasing it. Also, its price is significantly lower, so if you have a limited budget, this drug should definitely be your choice.

It’s only important to use Adrafinil as recommended, in the right dosage, and not to combine it with any other drugs because of the potential toxicity. Use it only for a short period of time, and don’t overstep the dosage in order to avoid damaging your liver. If this is something that worries you, then go with Modafinil – this drug doesn’t have this sort of implications.


How long do Modafinil and Adrafinil last?

It will be an hour, hour and a half after you take Modafinil for it to start working, while the waiting time for Adrafinil can be a bit longer – up to two hours. After that, you can expect to enjoy all the benefits of both drugs for the next nine to 12 hours. That’s the reason you should take your daily dosage in the early morning, so you can use the drug effect during the working hours, and to still be able to fall asleep at night, without facing insomnia.

Should I take Adrafinil or Modafinil every day?

When it comes to Adrafinil, it is recommended to use it every day, for a maximum of three weeks. The most common dosage is 300mg per day, but if you don’t believe that dosage delivers you all the benefits, you can increase the dosage up to 600 mg. But make sure never to consume more than that. 

After three weeks you should take a break for a minimum of one week and then continue with its usage. Modafinil, on the other hand, should not be consumed every day. It is recommended to take a daily dosage of 100mg to 200mg once to three times a week, or only in those situations where you need this sort of stimulation.

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